Do not take this medicine with any of the following medications:

-cisapride
-dronedarone
-fluconazole
-pimozide
-posaconazole
-saquinavir
-thioridazine
This medicine may also interact with the following medications:

-antiviral medicines for HIV or AIDS
-caffeine
-certain antibiotics like clarithromycin, erythromycin, telithromycin
-certain medicines for fungal infections like itraconazole, ketoconazole, voriconazole
-certain medicines for irregular heart beat
-certain medicines for seizures like carbamazepine, phenobarbital, phenytoin
-certain medicines that treat or prevent blood clots like warfarin
-dextromethorphan
-digoxin
-nefazodone
-midazolam
-other medicines that prolong the QT interval (cause an abnormal heart rhythm) like dofetilide, ziprasidone
-rifabutin
-rifampin
-rifapentine
-St. John''s wort, Hypericum perforatum
-tizanidine

They need to know if you have any of these conditions:

-eye disease, vision problems
-heart disease
-history of irregular heartbeat
-history of low levels of calcium, magnesium, or potassium in the blood
-kidney disease
-liver disease
-recent or ongoing radiation therapy
-an unusual or allergic reaction to vemurafenib, other medicines, foods, dyes, or preservatives
-pregnant or trying to get pregnant
-breast-feeding

Visit your doctor for regular check ups. You will need to have blood work while you are taking this medicine.
This medicine may cause serious skin reactions. They can happen weeks to months after starting the medicine. Contact your health care provider right away if you notice fevers or flu-like symptoms with a rash. The rash may be red or purple and then turn into blisters or peeling of the skin. Or, you might notice a red rash with swelling of the face, lips or lymph nodes in your neck or under your arms.
Talk to your doctor about your risk of cancer. You may be more at risk for certain types of cancers if you take this medicine.
Tell your doctor or health care provider right away if you have any change in your eyesight.
This medicine can make you more sensitive to the sun. Keep out of the sun. If you cannot avoid being in the sun, wear protective clothing and use sunscreen. Do not use sun lamps or tanning beds/booths.
Do not become pregnant while taking this medicine and for 2 weeks after your last dose. Women should inform their doctor if they wish to become pregnant or think they might be pregnant. There is potential for serious side effects to an unborn child. Talk to your health care provider or pharmacist for more information. Do not breast-feed an infant while taking this medicine and for 2 weeks after your last dose.

Keep out of the reach of children.
Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Keep this medicine in the original container. Keep tightly closed. Throw away any unused medicine after the expiration date.