Epinephrine

Medically Reviewed by Dr. Harshi Dhingra, M.D.

Last Reviewed: Mar 28, 2024

Side Effects


Epinephrine Side Effects

Common side effects of epinephrine are listed below. Tell your doctor if these side effects are severe when you obtain emergency medical care after an allergic reaction.

  • Injection site reaction with skin redness, swelling, tenderness, or warmth
  • Fast, pounding, or irregular heartbeat
  • Difficulty breathing
  • Dizziness
  • Sweating
  • Nausea
  • Vomiting
  • Restlessness, nervousness, or anxiety
  • Pale skin
  • Weakness
  • Uncontrolled shaking
  • Headache

The above list may not include all the potential adverse effects of epinephrine. Contact your healthcare professional if the side effects are unusual or severe or they do not get better over time. You can also report unusual side effects to the Food and Drug Administration at 1-800-FDA-1088.

Epinephrine Overdose: In case of an overdose, call your doctor immediately. You can also call your local poison control center or the national poison control center at 1-800-222-1222. Call 911 if a person cannot be awakened, has trouble breathing, has collapsed, or has had a seizure. Signs and symptoms of an epinephrine overdose may include pale or cold skin, tiredness, sudden weakness or numbness on one side of the body, confusion, sudden problems with speaking, fast breathing, shortness of breath, and decreased urination.

Source: FDA