Promethazine-Codeine

Medically Reviewed by Dr. Harshi Dhingra, M.D.

Last Reviewed: Feb 21, 2025

Directions


How To Use Promethazine-Codeine

Promethazine with codeine comes in the form of a syrup to be taken by mouth every 4-6 hours as needed for temporary relief from allergy and common cold symptoms.

Read the prescription label carefully and take the medicine exactly as prescribed. Do not increase the dose or dosage frequency without your doctor’s advice. Taking more than the recommended amount of this medicine can result in serious breathing problems. If your cough symptoms do not improve after taking promethazine with codeine for 5 days, call your doctor.

Use a dose-measuring device (cup or syringe) to measure the correct dose of liquid medicine. Do not use a regular household spoon - this can result in an accidental overdose. Do not overfill the dose-measuring cup or syringe. Wash the dosage syringe or cup with water after every use.

Missed dose: Promethazine with codeine is taken as needed for symptom relief. If you are taking it on schedule and miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next dose according to your regular dosing schedule. Do not take a double dose or extra medicine to make up for a missed dose.

Storage: Store promethazine with codeine at room temperature (between 15-30° C or 59-86° F) away from moisture, heat, and direct light in its original container, tightly closed. Do not store medications in the bathroom where they can be exposed to moisture and heat. Keep all medications safely out of reach of children and pets.

Unused medicine: Unused promethazine and codeine should be disposed of in a way that children, other people, and pets cannot get to them. Do not throw leftover medication in the trash or flush it down the toilet. The best way to dispose of expired or unneeded promethazine with codeine is through a medicine take-back program or your local waste disposal company. Learn more about proper medication disposal

NOTEThis medication guide is a summary and may not contain all possible drug information on promethazine with codeine. The drug information contained here may not be up-to-date. This sheet is for information purposes only. If you have questions about promethazine with codeine, talk to your doctor for medical advice.


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