Promethazine-Codeine

Medically Reviewed by Dr. Harshi Dhingra, M.D.

Last Reviewed: Feb 21, 2025

Pros & Cons


Promethazine-Codeine Pros and Cons

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  • The combination of promethazine and codeine is effective in controlling symptoms of allergies and the common cold.
  • It starts working within 30 minutes.
  • There is a lower-cost generic available.

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  • Promethazine and codeine combination is not safe for children.
  • It can interact with many other medications.
  • This drug carries a risk of serious and potentially life-threatening breathing problems.
  • It is a controlled substance, and you need to fulfill certain requirements to get a prescription.