Medically Reviewed by HaVy Ngo, Pharm.D.

Last Reviewed: Jun 13, 2022

Pros & Cons


What are the pros and cons of Seroquel (quetiapine)?

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  • Extended-release formulation is available for once-daily dosing, which is great for compliance and convenience.
  • Seroquel XR is well-tolerated and effective as monotherapy for individuals with acute manic episodes.
  • A lower-cost generic is available.
  • Can be used in both adults and children for the treatment of bipolar disorder and schizophrenia.

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  • Can cause high blood sugar, high cholesterol, and weight gain.
  • Can cause serious, life-threatening side effects, or even death in older patients with dementia-related psychosis
  • Increased risk of suicidal thoughts and ideations in young adults who are 24 years or younger.